PocketPCR Machine

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PocketPCR is a palm-size USB powered PCR thermocycler for amplifying DNA and molecular biology.


Simpler, smaller and more affordable. This ultra portable and compact thermocycler was designed with the goal to bring the cost down to affordable price for anyone who wants to do some biology with a DNA starter kit.




  • PID temperature control 

  • Temperature range: Ambient to 99°C

  • Technology: Resistive Heating, assisted cooling

  • USB powered from any 2A power adapter or computer port

  • Sample Tubes: 5 x 0.2ml PCR tubes

  • Small size of 33mm x 105mm x 50mm

  • Weight: 50 grams


This PCR machine does not have a heated lid and mineral oil is required to prevent sample evaporation. Mineral oil comes with kit. 

Runs from a 2A USB power plug and USB-C cable (not included).




PocketPCR is open source:


What's in the PCR Add-On Kit?

PCR Kit Add-On let's you get started right away with materials to look at your own DNA for what version of the DRD4 gene you have. This gene is associated with novelty seeking and risk taking.

The kit contains:

1-10uL pipette and 96 tips

~100 PCR Tubes

300uL 6x Dual Color Loading Buffer

50uL DNA Ladder 100bp 

50uL DNA Ladder 1Kbp

500uL 2x Taq Polymerase Master Mix

50uL DNA Safe Gel Stain

5g Agarose

25g TAE Buffer

DRD4 Primers 

10 - Cheek swabs


17.78 (cm)
17.78 (cm)
17.78 (cm)


  • 5

    Posted by Anders Hansson on 27th Sep 2021

    With help from our Makerspace, scrap and USD120, I am now in the process of building a 7x7 icewater-cooled programable PCR-machine.

  • 5
    Mini PCR cycler

    Posted by Dan on 8th Dec 2020

    Easy to program, works well and it's all that's needed for small experiments, as five tubes is more than enough. One can also find a nice top cover for it on Thingiverse.